NEW BATCH OF KETOSPIKE COFFEE WITH IMPROVED PACKAGING ARRIVED

INGREDIENTS

KETOSTART/ NO CAFFEINE/ TROPICAL FLAVOR                       KETOSTART+/ WITH CAFFEINE/ RASPBERRY LEMONADE FLAVOR

Ketone salts contain BHB bound to mineral ions, creating a balanced electrolyte formulation with a superior fuel energy molecule

The main ingredient in KETOSTART is D,L-Beta-Hydroxybutyrate /BHB/

The most abundant of the ketone bodies, beta-hydroxybutyrate (BHB), serves as an alternative fuel source to glucose and free fatty acids. It has been demonstrated that burning ketones, such as BHB, can yield more ATP (cellular energy currency) per unit oxygen, compared to glucose. In fact, ketones can generate 25% more energy than glucose. They have a “higher metabolic efficiency,” and have a greater “heat of combustion”, meaning they release more energy per molecule. In other words, the e.g. muscle tissue become more efficient, requiring less O2 for the same amount of mechanical work.

In addition, when our mitochondria are hard at work supplying energy in the form of ATP, reactive oxygen species (ROS) are made, and these molecules contribute to what is called “oxidative stress,” which puts both the mitochondria and other cell components, including our DNA, at risk for damage. Ketones have been shown to suppress the production of mitochondrial ROS, as well as help our cellular antioxidant defense systems to disarm ROS before they can cause damage.

So, when people are referring to ketones as a cleaner, more superior fuel source, they are often referring to their capacity to generate greater amounts of ATP and emit less (potentially damaging) by-products naturally produced during mitochondrial energy metabolism.

BHB can also be produced outside of the body and taken as a supplement, these are called “exogenous” ketones. Normally, BHB is synthesized in the liver from fatty acids and it serves as an essential carrier of energy from the liver to peripheral tissues when the supply of glucose is too low for the body's energetic needs, such as during periods of prolonged exercise, starvation, or absence of dietary carbohydrates. Research shows that BHB is not only a passive carrier of energy, but also has cellular signaling functions. These signaling functions of BHB work at the cell surface and inside the cells too, which can affect, for example, gene expression (epigenetic gene regulation), lipid metabolism, neuronal function, and metabolic rate.

WHY DOES KETOSTART CONTAIN D,L-BHB (racemic), NOT D-BHB?

Some might claim that D-BHB is superior, compared to D,L-BHB (or often called racemic), however, there are many benefits of L-BHB, so KETOSTART contains a mix of 1 to 1 ratio D- and L-BHB.

For example, L(S)-BHB is an important molecule as signaling, anti-inflammatory and epigenetic regulator.

L (S)-BHB-CoA is a transient intermediate in the final round of β-oxidation of fatty acids. Experiments involving infusions of labeled D(R)-BHB, S-BHB, or mixtures thereof into rats or pigs found that S-BHB is converted mostly to R-BHB; the molecular pathway for this is not known, but it may occur through conversion of S-BHB to acetyl-CoA and then production of R-BHB from acetyl-CoA. At least some of the S-BHB is eventually converted to CO2, presumably also after being metabolized to acetyl-CoA.

L (S)-BHB is metabolized much more slowly than D (R)-BHB is, so that consumption of the same amount of L (S)-BHB may result in higher and more sustained blood levels of S-BHB compared with a similar consumption of D (R)-BHB.

A recent study shows an important aspect of D,L-BHB supplementation, as L‐BHB concentrations increased extensively in the brain, heart, liver, and muscle tissues, whereas a less intense increase in D‐BHB was observed only in the heart and liver.

Another way L-BHB interacts with our immune system and may lower inflammation is by directly inhibiting the activation of the NLRP3 inflammasome, which has also been shown in cell culture studies. A recent study showed that this anti-inflammatory effect occurred in the presence of both D- and L-BHB. This can have important implications when considering that L-BHB stays in the bloodstream longer, and thus greater potential for suppressing chronic systemic and neuroinflammation. 

We also found D(R)-BHB ineffective for reducing seizure activity, while the mix of D,L-BHB was found effective, but certainly more scientific research is needed on this topic. This formulation was also found to be more GI tolerable.

Unfortunately, the currently available blood ketone meters are only able to detect D-BHB, and unable to measure L-BHB, so this can lead to a common misunderstanding. You actually have about twice as high BHB level in your blood than your blood ketone meter shows when you take a D,L mix BHB supplement, such as KETOSTART (as it is 1:1 ratio D and L BHB).

Read more about this topic here.

 

Balanced electrolytes to complement a healthy lifestyle

 

Ultimately, electrolytes are necessary for normal body functions, including heartbeat, brain function, muscle contraction and relaxation, and so much more. The need for supplementation increases when we cut carbs while transitioning to or following the ketogenic diet since the hormone insulin (which is suppressed on a ketogenic diet) plays a vital role in the kidney’s regulation of electrolyte levels, more specifically, sodium levels. When insulin levels fall, the kidneys retain less water and excrete more sodium in the urine, which can cause other minerals to become imbalanced. The ketogenic diet can also lead to increased water loss through glycogen loss (stored glucose). Every gram of glycogen stores around 3-4 grams of water, flushed out as glycogen is burned for energy, carrying electrolytes out with it. It is well-known that a ketogenic diet can lead to increased sodium excretion and water loss through the urine, which is associated with unwanted symptoms, such as fatigue, muscle cramps, and headaches, commonly called as “keto flu”. For this reason it is very important to replenish our electrolytes. KETOSTART will do just that, so you basically get 2 products in one: the necessary electrolytes in addition to the ketone energy molecules.

 

 

OTHER INGREDIENTS:

Sodium

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Calcium

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Magnesium Citrate

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Potassium Citrate

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Caffeine

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Citric Acid

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Malic Acid

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Natural Flavors

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Monk Fruit Extract

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Silicon Dioxide

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