About

(ɔˈdeiʃəs) ADJECTIVE   

Extremely bold or daring; recklessly brave; fearless:

AN AUDACIOUS explorer. extremely original; without restriction to prior ideas; highly inventive.

Showing a willingness to take surprisingly bold risks. This adjective is very bold — if you are audacious, you are daring and unconventional!

The adjective audacious comes from the Latin word audacia and means "daring, boldness, courage," and often gets applied in situations where someone does something pretty unusual, like becoming an astronaut and going to the moon. It can also mean challenging conventions and doing things that most people don't do.

Synonyms: DARING, VENTURESOME, VENTUROUS, ADVENTUROUS

KETOSTART/ NO CAFFEINE/ TROPICAL FLAVOR                       KETOSTART+/ WITH CAFFEINE/ RASPBERRY LEMONADE FLAVOR

Ketone salts contain BHB bound to mineral ions, creating a balanced electrolyte formulation with a superior fuel energy molecule

The main ingredient in KETOSTART is D,L-Beta-Hydroxybutyrate /BHB/

The most abundant of the ketone bodies, beta-hydroxybutyrate (BHB), serves as an alternative fuel source to glucose and free fatty acids. It has been demonstrated that burning ketones, such as BHB, can yield more ATP (cellular energy currency) per unit oxygen, compared to glucose. In fact, ketones can generate 25% more energy than glucose. They have a “higher metabolic efficiency,” and have a greater “heat of combustion”, meaning they release more energy per molecule. In other words, the e.g. muscle tissue become more efficient, requiring less O2 for the same amount of mechanical work.

In addition, when our mitochondria are hard at work supplying energy in the form of ATP, reactive oxygen species (ROS) are made, and these molecules contribute to what is called “oxidative stress,” which puts both the mitochondria and other cell components, including our DNA, at risk for damage. Ketones have been shown to suppress the production of mitochondrial ROS, as well as help our cellular antioxidant defense systems to disarm ROS before they can cause damage.

So, when people are referring to ketones as a cleaner, more superior fuel source, they are often referring to their capacity to generate greater amounts of ATP and emit less (potentially damaging) by-products naturally produced during mitochondrial energy metabolism.

BHB can also be produced outside of the body and taken as a supplement, these are called “exogenous” ketones. Normally, BHB is synthesized in the liver from fatty acids and it serves as an essential carrier of energy from the liver to peripheral tissues when the supply of glucose is too low for the body's energetic needs, such as during periods of prolonged exercise, starvation, or absence of dietary carbohydrates. Research shows that BHB is not only a passive carrier of energy, but also has cellular signaling functions. These signaling functions of BHB work at the cell surface and inside the cells too, which can affect, for example, gene expression (epigenetic gene regulation), lipid metabolism, neuronal function, and metabolic rate.

WHY DOES KETOSTART CONTAIN D,L-BHB (racemic), NOT D-BHB?

Some might claim that D-BHB is superior, compared to D,L-BHB (or often called racemic), however, there are many benefits of L-BHB, so KETOSTART contains a mix of 1 to 1 ratio D- and L-BHB.

For example, L(S)-BHB is an important molecule as signaling, anti-inflammatory and epigenetic regulator.

L (S)-BHB-CoA is a transient intermediate in the final round of β-oxidation of fatty acids. Experiments involving infusions of labeled D(R)-BHB, S-BHB, or mixtures thereof into rats or pigs found that S-BHB is converted mostly to R-BHB; the molecular pathway for this is not known, but it may occur through conversion of S-BHB to acetyl-CoA and then production of R-BHB from acetyl-CoA. At least some of the S-BHB is eventually converted to CO2, presumably also after being metabolized to acetyl-CoA.

L (S)-BHB is metabolized much more slowly than D (R)-BHB is, so that consumption of the same amount of L (S)-BHB may result in higher and more sustained blood levels of S-BHB compared with a similar consumption of D (R)-BHB.

We also found D(R)-BHB ineffective for reducing seizure activity, while the mix of D,L-BHB was found effective, but certainly more scientific research is needed on this topic. This formulation was also found to be more GI tolerable.

Unfortunately, the currently available blood ketone meters are only able to detect D-BHB, and unable to measure L-BHB, so this can lead to a common misunderstanding. You actually have about twice as high BHB level in your blood than your blood ketone meter shows when you take a D,L mix BHB supplement, such as KETOSTART (as it is 1:1 ratio D and L BHB).

Balanced electrolytes to complement a healthy lifestyle

Ultimately, electrolytes are necessary for normal body functions, including heartbeat, brain function, muscle contraction and relaxation, and so much more. The need for supplementation increases when we cut carbs while transitioning to or following the ketogenic diet since the hormone insulin (which is suppressed on a ketogenic diet) plays a vital role in the kidney’s regulation of electrolyte levels, more specifically, sodium levels. When insulin levels fall, the kidneys retain less water and excrete more sodium in the urine, which can cause other minerals to become imbalanced. The ketogenic diet can also lead to increased water loss through glycogen loss (stored glucose). Every gram of glycogen stores around 3-4 grams of water, flushed out as glycogen is burned for energy, carrying electrolytes out with it. It is well-known that a ketogenic diet can lead to increased sodium excretion and water loss through the urine, which is associated with unwanted symptoms, such as fatigue, muscle cramps, and headaches, commonly called as “keto flu”. For this reason it is very important to replenish our electrolytes. KETOSTART will do just that, so you basically get 2 products in one: the necessary electrolytes in addition to the ketone energy molecules.

OTHER INGREDIENTS:

FAQ

Csilla Ari D`Agostino, Ph.D.

"Being a neuroscientist, one of my main passion has been to better understand how our brain works and how could we improve its health and functions. As a Research Assistant Professor at the University of South Florida, I have been studying metabolic therapies in the last 12 years, specifically researching and optimizing ketone molecules for different applications. During these years of research, after publishing many scientific publications and making several discoveries in the field of ketones that resulted in multiple patents, I began to realize that not all ketone molecules were created equal. While researching the beta-hydroxybutyrate (BHB) molecule and seeing all the amazing effects, - even at the cell and molecular levels-, on optimizing health and performance, I became more and more convinced that I really should be consuming these molecules....many companies were selling exogenous ketone products by then, but my husband, Dr. Dominic D`Agostino and I felt that none of the available products were optimized and formulated ideally, we could not find any to recommend to people and I certainly did not find any that I felt both efficacious and enjoyable enough. We also knew that many people felt the same way. A couple years went by when finally I became frustrated to the point that I decided, I will embark on this unknown and risky journey of starting my own business and to develop the ideal ketone supplement, a highly potent, premium quality, but still enjoyable formulation without unpleasant side effects. My goal was to eliminate all the negative aspects I encountered while testing dozens of other ketone supplements on the market, while still delivering a high dose of BHB in a great tasting product. I was not in a hurry; all I knew was that I just wanted to do it right!

My husband`s research and his deep knowledge on this topic was an inspiration and a great influence that led me to this decision, although creating the products of such high standards seemed like a demanding and “audacious” journey, a project that I finally embarked on alone.

In 2017 the University of South Florida enrolled me in the National Science Foundation's Innovation Corps, which program was initiated by the government to train academics/scientists to bring their inventions to the market, so the public can actually benefit from them. My team completed the program at regional and national levels, but entering into the business world seemed even more intimidating.

Luckily, a long-time friend with huge amount of business experience, Ron Penna
(co-founder of Quest Nutrition and Legendary Foods) offered me his help to guide
me on this journey and he walked me through over the years step-by-step how to create
high quality products in an efficient and smart way. His encouragement and support convinced me to dare to take even if tiny steps and slowly, but to move forward to create the products I envisioned, in the business world that often felt like walking on a minefield. Audacious Nutrition was born and the KetoStart products were launched on July 3rd, 2021. Getting all the amazing
feedback from people who previously had negative experiences with other ketone supplements and whose lives are now changed by the Audacious Nutrition products made all the years of work already worth it and I can promise that this is just the beginning..."